MI Paste® & MI Paste Plus®
Topical Tooth Créme Containing Calcium, Phosphate & Fluoride

MI Paste and MI Paste Plus are the only products for professional use containing the active ingredient RECALDENT™ (CPP-ACP), a special milk-derived protein that has a unique ability to release bio-available calcium and phosphate (and fluoride in MI Paste Plus) to tooth surfaces. When it comes to maintaining a healthy smile, these key ingredients can make a big difference in overall health.
MI Paste Plus offers the same benefits of MI Paste, but is enhanced with a patented form of fluoride (900 ppm).
MI Paste and MI Paste Plus are safe and easy-to-use both in office and at-home. They are both available in five delicious flavors: melon, mint, strawberry, tutti-frutti and vanilla.
Choose MI Paste and MI Paste Plus with RECALDENT™ (CPP-ACP):
- Relieves tooth sensitivity
- Does not irritate dry mouths
- Helps minimize tooth sensitivity before and after professional cleaning and tooth whitening
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Casein Phosphopeptide (CPP) are natural occurring molecules which are able to release calcium and phosphate ions and stabilize Amorphous Calcium Phosphate (ACP), which is also the source of calcium and phosphate. | |
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MI Paste and MI Paste Plus are not toothpastes; they are topical tooth crèmes that can be used safely several times daily (or directed by your dental professional or physician). Both products release vital minerals into the mouth when and where needed. | |
*Images above: Electronmicrograph demonstrating occlusion of exposed dentinal tubules by CPP-ACP. CPP-ACP relieves sensitivity within 3-5 minutes. (Prof. E. Reynolds) |
What is the difference between MI Paste & MI Paste Plus?
MI Paste does not contain fluoride and is recommended for children under six years of age and pregnant women.
MI Paste Plus offers the same great benefits of regular MI Paste; it is enhanced with a patented form of fluoride.
- MI Paste and MI Paste Plus contain RECALDENT™ (CPP-ACP); Casein Phosphopeptide (CPP) are natural occurring molecules which are able to release calcium and phosphate ions and stabilize Amorphous Calcium Phosphate (ACP), which is also the source of calcium and phosphate
- RECALDENT™ (CPP-ACP) is a special milk-derived protein that can help decrease dentin hypersensitivity
- MI Paste and MI Paste Plus with RECALDENT (CPP-ACP) adheres easily to soft tissue, pellicle, plaque and even hydroxyapatite; they react similar to the mineral/statherin relation in saliva supplying bio-available calcium and phosphate (and also fluoride in MI Paste Plus) required for supersaturation to take place1,2
- MI Paste supplies calcium and phosphate needed for patients with poor saliva flow; this situation can be further augmented by elevating the level of fluoride (by using MI Paste Plus, which has fluoride)
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Applying at home:
- Brush with a fluoride toothpaste (1,000 ppm) in the morning
- Using a clean finger, apply a pea-sized amount of MI Paste or MI Paste Plus to the tooth surface
- Leave the mouth undisturbed for 3 minutes (repeat up to 4 times a day or as your dental professional recommends)
Applying at the dental office:
- Using a clean finger, apply a pea-sized amount of MI Paste or MI Paste Plus to the tooth surface
- If using a custom tray, take the custom tray and set in the mouth
- Leave the mouth undisturbed for 3 minutes
- Ask patient to avoid expectoration or swallowing for 2 minutes
1. Schupbach et al, “Incorporation of caseinoglycomacropeptide and caseinophosphopeptide into salivary pellicle inhibits adherence of mutans sreptoccoci,” J Dent Res, 1996; 75: 1779-88.
2 Rose, “Effects of an anticariogenic casein phosphopeptide on calcium diffusion in streptococcal model dental plaques,” Arch Oral Biol 2000; 45(7):569-75.
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Canada
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"Since I incorporated MI Paste into my practice, I have noticed a dramatic decrease in white spots...I now prescribe MI Paste for most of my patients as a preventive measure."
Dr. Michael Florman,
Santa Monica, CA
“I am amazed by the immediate relief of sensitivity. I now apply MI Paste immediately after every whitening procedure.”
Dr. Jeff Blank,
Rock Hill, SC
“MI Paste Plus is far and away the most effective treatment out there for generalized dentinal hypersensitivity.”
Dr. Brian Nový, Assistant Professor
Department of Restorative Dentistry, Loma Linda University School of Dentistry
Australia
“I personally treated my teeth using etchant for two 20 second intervals, followed by MI Paste in a tray at nighttime for 2 – 3 weeks. Very happy with the results!”
Dr. Stephanie M. Benton
“I have had beautiful results using MI Paste to treat ugly enamel lesions. This patient’s teeth were first etched and she then used MI Paste twice daily in a tray for three months. Before starting the third month with MI Paste, she first used Whitestrips for two weeks. Both the patient and I are incredibly happy!”
Dr. Ivan A. Serdar
“RECALDENT™ (CPP-ACP) technology has transformed my practice! I use MI Varnish™ and MI Paste™ because RECALDENT™ (CPP-ACP) technology offers a natural and unique system for releasing bioavailable calcium, phosphate and fluoride into the saliva. MI Varnish™ and MI Paste™ are an essential part of my practice.”
Dr. Pamela Maragliano-Muniz

Click here to view the video streaming on Vimeo!
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